Sequence-specific mr imaging findings that are useful in dating ischemic stroke

Sequence-specific mr imaging findings that are useful in dating ischemic stroke - Supplemental Content

Sequence-specific mr imaging findings that are useful in dat

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The significance of circulating miRNAs for early diagnosis of acute stroke in humans is unknown.

We aim to determine whether circulating miRNAs potentially serve as novel biomarkers for acute stroke. We prospectively recruited patients with acute stroke and those usefuo nonstroke disease. Patients with acute stroke were identified using magnetic resonance imaging MRI for early diagnosis.

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A total of patients were included in the study. Testing by miRNA microarray and real-time PCR analyses showed that hsa-miRb-5P and hsa-miR were present with markedly high abundance in patients of acute stroke, whereas hsa-miRe and hsa-miRd were present with ssquence-specific low abundance in patients compared with healthy individuals.

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Compared with healthy individuals, the miRNAs were increased as in patients with acute stroke as follows: Elevated hsa-miRb-5P and hsa-miR and decreased hsa-miRe and hsa-miRd in plasma may be novel biomarkers for the early detection matchmaking service saskatoon acute stroke in humans. The funders had thzt role in study design, data collection and analysis, decision to publish, or preparation of the article.

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